WILMINGTON, MA — The Wilmington Police Department recently had an incident of two individuals gaining access to a home posing as Water Department Employees. Several other area towns have had similar incidents. A Wilmington resident called 911 after two men came to the residence posing as contractors for the Water Department. They told the resident that they needed to do an emergency check of the water for lead contamination. In other cases, the males approach the resident and said that there was a water break in the area and that the resident’s water meter needed to be reset. These individuals will work together to attempt to distract the resident so the group may split up and gain access to the rest of the home.The Town of Wilmington Water Department employees operate town owned, clearly marked vehicles. If an individual approaches your residence or stops to ask questions regarding any utilities or permits, please ask for official town issued identification or call the Wilmington Police Department to verify whether the person is affiliated with the town. You may also contact the Wilmington Department of Public Works at 978-658-4481 during normal business hours. In almost all cases, the Town of Wilmington will notify residents if Water Department employees need to gain access to a residence prior to the visit.Elderly residents are most often the targets of these types of scams. We want to ask our residents to take a moment to speak with elderly parents and neighbors so they are on the alert for this type of unscrupulous activity.(NOTE: The above press release is from the Wilmington Police Department.)Like Wilmington Apple on Facebook. Follow Wilmington Apple on Twitter. Follow Wilmington Apple on Instagram. Subscribe to Wilmington Apple’s daily email newsletter HERE. Got a comment, question, photo, press release, or news tip? Email email@example.com.Share this:TwitterFacebookLike this:Like Loading… RelatedWilmington Police Officers Recognized By US Attorney’s OfficeIn “Police Log”POLICE LOG for May 23: Police Arrest 4 Individuals; Shoplifting At Market Basket Leads To Drug ArrestsIn “Police Log”SELECTMEN NEWS: Board Supports Fire & Police Substation In North Wilmington; Town To Vote On Project In April 2020?In “Government”
Singapore’s budget airline Scoot is currently increasing its presence in India’s domestic aviation sector. The long-haul budget arm of Singapore Airlines has launched its operations in Jaipur as its third destination.Scoot started its India operations in May this year when it launched flight to Amritsar and Chennai with a Boeing 787 plane. The airline will fly to Jaipur three times a week, which would increase to four from this month end, Press Trust of India reported.”We are excited to welcome an international airline like Scoot as it opens new avenues for the public in Jaipur to fly to popular destinations. This will go a long way in boosting trade and tourism for the city making it more prominent on the world map,” Vasundhara Raje, Chief Minister of Rajasthan was quoted as saying by the agency.Other subsidiaries’ SilkAir and Tigerair also fly to India.”We are a very young airline, just four years old, but have always been interested in the Indian market. Last year, when aircraft deliveries started coming in, we have been eyeing Indian market. We started the ground work early last year to commence operations here,” Bharath Mahadevan, country head of Scoot airlines had said in a statement in May.The airline hopes to double its operations in terms of cities by 2017.In May 2014, parent company Singapore Airlines (Asia’s biggest carrier by market value) spent $319 million in buying stock in Scoot Pte, Bloomberg reported.
In picture: Israel Prime Minister Benjamin Netanyahu meets Prime Minister Narendra Modi. [File Photo]Press Information BureauIsraeli Prime Minister Benjamin Netanyahu is scheduled to come to India on an official visit within two weeks. Netanyahu will visit India for a day just a week before Israel goes to repeat polls after he failed to form a government following the April 9 elections.The Israeli PM will meet his Indian counterpart Narendra Modi where the two leaders are expected to discuss issues including the acquisition of two more Airborne Warning and Control Systems (AWACS), extended range air to air Derby missiles by the Indian Air Force and joint projects in agriculture, water, and waste management.Apart from Military discussions, Netanyahu is expected to extend his support to the Indian government’s abrogation of articles 370 and 35A in Kashmir, as an internal matter and support the bilateral resolution of issues between India and Pakistan. Citing Top diplomats, Hindustan Times reported that before his arrival an advanced security liaison team from Israel will come to Delhi on September 2 to prepare grounds. However, the date of Netanyahu’s arrival is yet to be finalised but he is expected to come either on September 7 or 8.Political pundits have argued saying that Netanyahu’s meeting with PM Modi is more symbolic in nature to enhance his image before the general election. Earlier this year in July, Netanyahu became the longest-serving Israeli prime minister, surpassing Israel’s first premier David Ben-Gurion. Notably, his ruling Lukid party is facing a tough challenge with flagging fortunes. Personally, also the Israeli PM is fighting for personal survival ahead of a hearing before the state prosecution on several graft cases. Israeli Prime Minister Benjamin Netanyahu gestures as he speaks during an event marking “The Appreciation for the Fallen of Israel’s Wars and Victims of Terrorism Day” at the Knesset, Israeli parliament, in JerusalemREUTERS/Ammar AwadIndian is planning to buy $2 billion worth two PHALCON AWACS mounted on Russian A-50 platform for better surveillance in the air. The order is yet to be approved from the Cabinet Committee on Security (CCS). India has five AWACS platforms in comparison to Pakistan, which already has seven in its armada. Moreover, Pakistan has ordered three more from China. Pakistan is already operating three SAAB Erieye and four ZDK-03 from China, which were airborne 24X7 after the Balakot airstrike by the Indian Air Force on JeM camps. On the other hand, IAF deployed AWACS for only 12 hours period.Apart from acquiring two AWACS, India also plans to buy extended range Derby air-to-air missiles from Israel. IAF wants to further upgrade Su-30 MKI with integrating the 70-kilometre range Derby missiles on its platform with the latest radar equipped with a data link to engage with Pakistani F-16s in future.
A devastating fire breaks out at a building at Chawkbazar in the capital on Wednesday night. Fire fighters try to douse as fire spreads to nearby buildings. Photo: Focus BanglaThe home affairs ministry has formed a 5-member committee to investigate into the Chawkbazar fire incident that left nearly 80 people dead.Headed by additional secretary of security service division of the home ministry the committee was asked to submit its report with recommendations within seven working days after proper investigation, said an official release, reports UNB.Around 41 people injured in a devastating fire that broke out at a chemical warehouse and raged through four other adjacent buildings in the city’s Chawkbazar area on Wednesday night.
Share Photo via PixabayThe U.S. Department of Agriculture on Thursday announced the recall by PFP Enterprises, also operating as Texas Meat Packers.A Fort Worth meatpacker is recalling nearly 4 tons of ground beef products that contain soy but the allergen is not listed on the labels.The U.S. Department of Agriculture on Thursday announced the recall by PFP Enterprises, also operating as Texas Meat Packers.The recall includes 40-pound cases containing four 10-pound bags of “85/15 Ground Beef Bulk” with item code 4013 and labeled Patterson Food Processors. The recall also includes 10-pound cases containing two 5-pound bags of “85/15 Ground Beef Bulk” with item code 4012 and labeled Patterson Food Processors.The raw, frozen items were produced Sept. 28 and have “EST. 34715” inside the USDA mark of inspection.The USDA has no reports of anyone getting sick. Recalled items should be discarded or returned to the place of purchase.
Despite efforts across the region to remove both vestiges of Confederate history and polarizing U.S. figures memorialized in public spaces, the District remains home to several, including a highly controversial statue of Brig. Gen. Albert Pike situated at Judiciary Square – between D.C. Courthouses and the Labor Department. And while hidden in plain view, even “conscious” Blacks seem largely unfazed by the towering figure as they enjoy meals and lunch-time strolls around the grounds.The statue of Brigadier General Albert Pike, a Confederate and Klansman, sits near the Judiciary Square metro station, and remains overlooked by many Blacks in the area.(Photo by Shantella Y. Sherman)The six-foot, 300-pound Pike, according to his Smithsonian Associates biography, not only gained notoriety as a teacher, journalist, Brig. Gen. during the Confederacy, and U.S.-Native American treaty negotiator, but also as a Klansman, who has been credited with creating the rituals of the Ku Klux Klan for its founder Nathan Bedford Forest.“It’s ironic that in a city that was once majority African-American and which is still home to some of the most justice-minded residents, a constant stream of people of all races sit around this statue and eat, talk, and socialize,” Edith Grey-Scott, a Ward 7 resident and long-time Judiciary Square vendor told the AFRO. “There have been protests in the past to have the monument to Pike removed, but the passion for the fight waned.”While Pike is the only Confederate Civil War general memorialized in D.C., calls for its removal began in 1991 – with the D.C. Council unable to reach a decision about its razing. Weekly protests by Lyndon LaRouche, a political activist, continued through 1992, but eventually ended.The statue was erected in 1901, some 10 years following Pike’s death, by fellow Freemasons, who considered his efforts on behalf of their organization both significant and valiant.Congress Heights resident Carlos Payton, who walks the path surrounding Pike’s statue during his lunch breaks, said he never paid much attention to the figure – assuming it honored someone of importance to the history of the District or the courthouses. Upon learning of Pike’s connections to the Confederacy and the Klan, Payton was taken aback.“That’s unreal. All these Black people around here and this racist guy is peering down at us as we go about our day… I guess we need to get the statue removed, but also learn a lot more about the history of these parks and monuments surrounding us,” Payton told the AFRO. “We’ve got our children fighting in the streets for Black Lives Matter, and the whole time, as parents, we’re working around monuments to people who initiated some of these plans to oppress us.”In addition to Pike’s statue, the National Statuary Hall Collection housed on U.S.Capitol grounds, contain 13 statues of Confederate figures, including Jefferson Davis, Robert E. Lee, and Edmund Kirby Smith.
Implementing the single-molecule DNA navigator. a) Schematic illustration of the PSEC system. An acyclic connected graph (i.e. a tree) is constructed on a rectangular DNA origami substrate of 100 x 70 nm^2. T1 and T2 are two types of fuels driving the PSEC on the tree. Initiator I was used to trigger the initiation of the PSEC from the entrance vertex ENT. b) propagation mechanism of the PSEC system. Initiator I recognizes and opens the T1ent hairpin at vertex ENT. The opened hairpin then captures and opens a T2 hairpin from the environment to start the cascade. c) A straight line paved by PSEC and visualized with DNA-PAINT. d) Four paved digits of “2017” imaged using atomic force microscopy (AFM). The T1 hairpins at the corner points were modified to prevent unwanted spans. The arrows indicate the direction of propagation. Credit: Nature Materials, doi: 10.1038/s41563-018-0205-3. © 2018 Science X Network Tying the knot: New DNA nanostructures , Science In the present study by Chao et al, the same basic principle of the HCR reaction scheme was used in a different computational context to develop a single-molecule DNA-navigator system. The platform explored all possible paths through a tree graph designed on an origami structure as a simply connected maze without cyclic paths. Such DNA origami structures are information-bearing nanostructures by nature with well-defined nanoscale geometry. The maze could be explored by proximal strand exchange cascade (PSEC) based on hybridization chain reactions. The researchers demonstrated that a system with a large number of single-molecule DNA navigators could collectively conduct parallel depth-first search (PDFS) on the tree to efficiently perform maze solving within 2-D origami. Initially the researchers conducted studies to test the PSEC design. Journal information: Nature Materials Citation: Solving mazes with single-molecule DNA navigators (2018, November 16) retrieved 18 August 2019 from https://phys.org/news/2018-11-mazes-single-molecule-dna.html More information: Jie Chao et al. Solving mazes with single-molecule DNA navigators, Nature Materials (2018). DOI: 10.1038/s41563-018-0205-3Renjun Pei et al. Training a molecular automaton to play a game, Nature Nanotechnology (2010). DOI: 10.1038/nnano.2010.194S. M. Douglas et al. A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads, Science (2012). DOI: 10.1126/science.1214081 Kinetics of the process were investigated at the single-molecule level in the study using time-resolved total internal reflection fluorescence microscopy (TIRF) in a setup with a prescribed starting point (P0) and five intermediate steps (P1-P5). Fluorescence in the setup was quenched using fluorescence resonance energy transfer (FRET), and the cascade was observed in real time by recording fluorescence signals continuously. The average speed of propagation was recorded to be 2.46 nm per minute, propagation across the straight line (54.4 nm) took approximately 22 minutes. The scientists then constructed the main model maze with 10 vertices that included an entrance vertex A and an exit vertex J, three junctions (B, D, E) an intermediate vertex (I) and four dead ends (C, F, G, H). Each path of the maze that was equivalent to a tree with 10 vertices was investigated using DNA investigators starting at root A. The PSEC reactions produced a mixture of various paths on the maze, confirmed with AFM. Each individual PSEC could progress on one of the five possible paths. Statistical analysis of the length distribution showed that the measured paths coincided well with the values predicted. To prevent the navigators from propagating through a wrong path with dead ends, the scientists designed a streptavidin-biotin tag-based method to selectively eliminate inaccurate path navigation. Only the correct path (PABDIJ) was followed in the maze therefore. The computational context used in the study allowed exploration of paths through tree graphs defined on the origami. The autonomous path explored by the DNA navigators proceeded unidirectionally and irreversibly, turning at junctions and corners on the origami platform as they were designed to. The design enabled parallel depth first search (PDFS) allowing each DNA navigator to individually explore any one of the paths through the given graph at a defined speed, greater than that previously achieved. The main advantage of the described biomolecular computer schemes in comparison to conventional electronic computing is they can be interfaced directly with biologically relevant processes. As a result, the scientists envision translational biomedical sensing and decision-making platforms with DNA origami and single-molecule diagnostics using decision trees. Future applications will also include simple sensors or those coupled to a molecular actuator to trigger downstream molecular cascades. , Nature Nanotechnology Pathfinding operations with DNA navigators make use of a localized strand exchange cascade process initiated at a unique trigger site on the origami platform. Automatic progression along paths is enabled by DNA hairpins containing a universal traversal sequence. By design, each single-molecule navigator can autonomously explore any of the possible paths through a 10-vertex rooted tree constructed in the study. The mazes were equivalent to a tree with an entrance at the root and an exit through one of the leaves. The study conducted by Jie Chao and co-workers resulted in exploring all paths taken by the DNA navigators to extract a specific solution path that connected a given pair of start and end vertices in the maze. As a result, the solution path was laid plainly on the origami platform and illustrated using single-molecule imaging. The approach is now published in Nature Materials, detailing the realization of molecular materials with embedded biomolecular computational functions to operate at the level of the single-molecule with potential to engineer intelligent nanorobots for future applications in industry and medicine.Sophisticated molecular tools were used in the past to create molecular machines that convert chemical, photonic or electric energy into rotary or linear movements at the nanoscale. For instance, Brownian motion at the nanoscale can be controllably converted into directed movements within DNA-based nanomachines using DNA hybridization reactions. Such DNA-based machines operate autonomously by following an embedded ‘molecular program’ pre-designed as a cascade reaction manually triggered via an external stimulus for each step of the operation. The focus of the field has progressively shifted to actualize DNA-based logic circuits using aptamers and DNAzymes to design molecular logic gates. For example, in 2006, Stojanovic and co-workers integrated more than 100 DNA logic gates to engineer an automation calledMAYA-II to play a game of Tic-Tac-Toe. Preceding studies demonstrated an enzyme free computing system based on hybridization chain reactions (HCR) to create logic-gates and logic circuits for more robust and efficient performance than the original systems. Single-molecule DNA navigators for maze-solving. a) Schematic illustration of magnetic bead-based selection. Exit vertex J is labelled with biotin to enable differentiation between the correct and wrong paths. Only if the PSEC reaches the correct exit J, would the biotin-modified T1exit-B strand be released. All wrong paths could be captured and removed by the Streptavidin-modified magmatic beads therefore. b) Details of the release of biotin modification at the exit J by the PSEC. c) AFM characterization of the correct solution after selection. The remaining structures all showed the correct solution path PABDIJ. d) Single-molecule and class-averaged DNA-PAINT characterization of the correct solution after selection. Credit: Nature Materials, doi: 10.1038/s41563-018-0205-3. Explore further The proximal strand exchange cascade (PSEC) system (working principle of the DNA navigator) was facilitated on a rectangular origami substrate made of three components, which included the physical implementation of a tree graph, full strands and an initiator strand. Vacant areas without staple extensions corresponded to walls in the maze, preventing propagation of the strand exchange cascade. The entrance and exit were defined and denoted as ENT and EXIT respectively. In the second component, two types of DNA hairpins, T1 and T2, were used as fuels to drive the PSEC on the tree graph. The two hairpins coexisted metastably in solution to hybridize and fuel the PSEC process with free energy . By design, information only propagated through the network in the presence of an initiator (Initiator I). Upon addition of initiator I, PSEC was conducted and observed using atomic force microscopy (AFM). To visualize an established formation, the scientists enabled DNA-navigator-based formation of the number 2017 as a proof-of-principle. Another technique known as DNA-PAINT was employed as a single-molecule, super-resolution imaging technique to reveal molecular features at the nanoscale to further substantiate the PSEC-based path paving process. The on-origami PSEC was highly specific, without intra- or inter-origami crosstalk. The field of intelligent nanorobotics is based on the great promise of molecular devices with information processing capabilities. In a new study that supports the trend of DNA-based information carriers, scientists have engineered a DNA navigator system that can perform single-molecule, parallel, depth-first search operations on a two-dimensional origami platform. Single-molecule characterization of PSEC kinetics. a) A straight line in the middle of the DNA origami was used as the test bed. Vertex P0 is the starting point and vertices P1-P5 are intermediate points. b) Details of the design of six parallel tests to measure the kinetics with time-resolved TIRF. T2 labelled with BHQ2 was used to quench T1 labelled with Cy3, assembling a kinetic profile at each step. The illustrated example shows the mechanism of quenching. c) Example TIRF images show the fluorescence changing with time across the six parallel tests from P0 to P5. d) Typical single-molecule fluorescence traces used to monitor quenching events occurring at vertices P0 to P5. e) Scatter plots showing statistical analysis of the length distribution per path. Credit: Nature Materials, doi: 10.1038/s41563-018-0205-3. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. The PSEC-driven graph traversal on a maze. a) A maze design with 10 vertices. Arrows indicate the entrance vertex A and exit vertex J. b) The maze is equivalent to a rooted tree with 10 vertices. The entrance vertex A corresponds to the root of the tree. c) An AFM image showed the result of a transversal experiment generating all possible paths. In this DNA computing implementation of a PDFS algorithm, a vast number of PSEC events simultaneously occurred to realize the graph traversal on the maze. PSEC ending at the exit or deadends were highlighted in red circles. Invalid structures were highlighted with white circles. d) Typical paths found in the mixture seen from left to right. Only PABDIJ was the correct solution to the maze. e) Scatter plots showing the statistical analysis of the length distribution for each path. Credit: Nature Materials, doi: 10.1038/s41563-018-0205-3.
You decide what you watch. That is the funda behind Humour Me’s Improv Nights. Here audience is the king as artistes will improvise on the spot in order to entertain you. Their one-hour performance on Sunday saw an entertaining stand-up performance where they improvised on the spot, spontaneously without any pre-written script. The audience drove the theme of each segment of the show. Humour Me is a group of four performers and one host. The artistes performing at Improv Nights are Dhruv Sachdeva, Clifford Alfonso, Andrew Hoffland, Pranay Manchanda and Shantanu Anam. Also Read – ‘Playing Jojo was emotionally exhausting’Dhruv Sachdeva takes up the role of the host and is also the founder of Humour Me and has been in the entertainment world for the past 10 years. He started his acting career with the role of Scar in the musical Circle of Life which is an adaptation of the Broadway musical The Lion King’ Last year, Dhruv produced and acted in the production The Character of a Happy Life. And most recently, wrote, directed and acted in an original musical theatre production Also Read – Leslie doing new comedy special with NetflixDinner for Pricks, under the Humour Me banner.So the audience gives them a situation or a scene to enact, and they perform it on the spot — with sound effects and even mimicry et al in place.‘We basically perform as per the demand of the audience which includes different dance forms like rap, conventional etc and various music genres too,’ said Dhruv.Clifford started years back with the musical production Noah’s Ark. Andrew Hoffland, oldest of all the performers, works as a teacher and has been singing and acting in various theatrical and musical productions. Pranay Manchanda has been an actor for over 15 years, and has worked in theatre.Shantanu Anam has worked as is an actor from the age of 16, and has acted and directed several theatre productions. ‘We are here to deliver happiness, not shoes. If we don’t stick in your mind, we consider we have have failed,’ said Dhruv. Fair enough!DETAILAt: Lure Switch, Lado Sarai when: 23 December
In the age of mobile devices such as smartphones and tablets, young children are spending more time watching television than ever before, according to a study. Researchers from Florida International University in the US compared pre-mobile device usage in 1997 to when mobile devices were widely available in 2014. The study, published in the journal JAMA Pediatrics, found that television consumption still significantly outpaced mobile devices such as smartphones or tablets. Also Read – Add new books to your shelf”There is growing concern over the amount of time that children, particularly very young children, spend watching shows and in front of screens,” said Weiwei Chen, an assistant professor at Florida International University. “Our findings were surprising as it feels like mobile devices are omnipresent, but televisions are still the most common way for young children to consume media,” Chen said. The recently conducted study found that the average amount of screen time in 1997 for children up to the age of two was 1.3 hours while children between the ages of three and five spent about 2.5 hours a day on screens. Also Read – Over 2 hours screen time daily will make your kids impulsiveBy 2014, children up to the age of two were using screens an average of three hours per day – more than double the amount of time. This study is unique as it uses written diary data provided by parents instead of general surveys that are often administered at a later date, which may cause a greater parental recall bias. “The increase in the amount of screen time for infants and toddlers is telling. Our study reinforces general findings that a variety of characteristics, such as education and income levels, relate to screen use,” said Jessica L Adler, an assistant professor at Florida International University. “Further research is needed, once data become available, to assess changes in media consumption and device use in more recent years,” Adler said. While there is much concern about the overuse of mobile devices to occupy and entertain children, it is important that more attention be paid to the amount of television they are consuming, according to the researchers.
Full list of roadworks M6, A500 and A50 Bridge to close for seven months Stoke-on-Trent Stafford Borough, Rugeley, Uttoxeter Staffordshire Moorlands South Cheshire Get the biggest Daily stories by emailSubscribeSee our privacy noticeThank you for subscribingSee our privacy noticeCould not subscribe, try again laterInvalid EmailDrivers are being warned to expect traffic and travel delays due to roadworks across North Staffordshire and South Cheshire this coming week. Motorists hitting the roads of Stoke-on-Trent and the surrounding areas on Monday morning can expect a raft of delays and road closures waiting for them – including on major routes such as the M6 motorway, the A500 and the A50. The following roadworks are taking place in North Staffordshire and South Cheshire between Monday October 22 and Sunday October 28. This list contains only the roadworks considered to be most likely to cause delays on key routes as well as those involving road closures and temporary traffic lights. It is not exhaustive and does not feature some minor or emergency repairs that come up after publication. Other roadworks may finish or start before schedule or be cancelled altogether. The list is broken down by local authority area (Stoke-on-Trent, Newcastle Borough, Staffordshire Moorlands and Stafford Borough) – with the M6 , A500 and A50 separate because they fall under the remit of Highways England), and a section on roadworks near Uttoxeter for anyone who lives or works in the East Staffordshire town. If you only want information about roadworks in a particular area click the links below, or scroll down for the full lists. All information from Highways England, local authorities and utility companies. Read MoreRoadworks from October 22 until October 28 M6 (from Junction 19 to Junction 12, listings north to south): The M6 southbound between junctions J19 and J18: Three lanes closed from 22:00 on 20 October 2018 to 06:00 on 21 October 2018 The M6 northbound exit slip at junction J19: Expect disruption everyday between 22:00 and 06:00 from 22 October 2018 to 3 November 2018. Two lanes closed The M6 southbound exit slip at Knutsford Services: From 22:00 on 20 October 2018 to 06:00 on 21 October 2018. One lane closed. The M6 northbound between junctions J18 and J19: Expect disruption everyday between 22:00 and 06:00 from 22 October 2018 to 3 November 2018. Three lanes closed. The M6 southbound exit slip at junction J18: From 22:00 on 20 October 2018 to 06:00 on 21 October 2018. Two lanes closed The M6 northbound exit slip at junction J17: From 22:00 on 25 October 2018 to 06:00 on 26 October 2018. Two lanes closed The M6 northbound entry slip at junction J16: Expect disruption everyday between 22:00 and 06:00 from 23 October 2018 to 25 October 2018. Two lanes closed The M6 northbound exit slip at junction J16: From 22:00 on 22 October 2018 to 06:00 on 23 October 2018. Two lanes closed. The M6 northbound entry slip at junction J14: Expect disruption everyday between 21:00 and 06:00 from 29 October 2018 to 3 November 2018. Two lanes closed Revealed: Extra 20,000 GP appointments are being created under £600k plan to ease winter pressure in Stoke-on-Trent A500 (from junction with J16 of the M6 to junction 15 of the M6, listings north to south): Northbound from A527: Two lanes closed from 21:00 on 24 October 2018 to 04:30 on 25 October 2018 The A38 northbound exit slip to the A50: Expect disruption everyday between 19:30 and 05:00 from 22 October 2018 to 27 October 2018. Two lanes closed. The A38 southbound exit slip to the A50: Expect disruption everyday between 19:30 and 05:00 from 22 October 2018 to 27 October 2018. Two lanes closed. A50 (from Sideway Roundabout/A500 to junction with the A38 (Toyota Island) in Derbyshire, listings west to east): The A50 eastbound entry slip from the A522: Expect disruption everyday between 09:45 and 16:00 from 22 October 2018 to 26 October 2018. One lane closed. The A50 eastbound exit slip to the A522: Expect disruption everyday between 09:45 and 16:00 from 22 October 2018 to 26 October 2018. One lane closed. Dozens of fed-up residents call for restrictions to BAN Stoke City fans from parking on their estate Stoke-on-Trent: A53: Roadworks and roadclosures on A53 Leek New Road from Horn and Trumpet public house to junction with Norton Lane/Newton Crescent, with work taking place overnight. Until October 22. Adderley Green: Give and take traffic control near the bus depot from October 23 until October 25 Bentilee: Multi-way traffic signals on Dividy Road between number 101 and number 171 from September 7 until December 7 Burslem: Give and take traffic control on Waterloo Road near junction with Bursley Road from October 24 until October 26 Burslem: Give and take traffic control on Waterloo Road near junction with Queen Street from October 24 until October 26 Chell: Roadworks and road closures on A527 Biddulph Road near junction with Peck Mill Lane from October 18 until November 2 Cobridge: Carriageway incursion on Leek New Road near Elder Road from October 23 until October 25 Cobridge: Give and take traffic control on Leek New Road near junction with Sandbach Road from October 17 until October 24 Dresden: Two way traffic signals on Cocknage Road near Chaplin Road from October 12 until November 8 Dresden: Roadworks and road closure on Belgrave Road from October 22 until November 2 Etruria: Carriageway incursion on Clough Street near The Kitchen and Bedroom Workshop from October 15 until October 22 Hanley: Roadworks and road closure on Slippery Lane until October 30 Hartshill: Two way traffic lights on B5045 Shelton New Road near rear of 12 Basford Court from October 18 until October 22 Hartshill: Two way traffic lights on B5045 Shelton New Road near number 476 from October 25 until October 31 Longton: Roadworks and road closures on Market Street and Commerce Street from June 5 until November 30 Longton: Carriageway incursion on King Street from October 16 until October 23 Northwood: Carriageway incursion on Bucknall Old Road from October 13 until October 22 Norton: Roadworks and some road closures on Bellerton Lane from October 18 until November 9 Reginald Mitchell Way: Give and take traffic controls on Reginald Mitchell Way near the A500 from October 25 until October 29 Shelton: Ashford Street closed until November 10 Shelton: Roadworks, traffic control and lane closures on Shelton New Road, Shearer Street, Bedford Road, Bedford Street, Lower Bedford Street, Davis Street and Lomas Street from October 19 until November 26 Stoke: Carriageway incursion on A5006 Campbell Road from October 18 until October 22 Stoke: Multi-way traffic signals on London Road near mini roundabout outside Port Meirion from October 4 until October 24 Stoke: Two way traffic signals on Stanley Matthews Way, near Stoke Audi, from October 28 until October 31 Stoke: Multi-way traffic lights on Stoke Road at the railway bridge from October 25 until October 26 Tunstall: Multi-way traffic lights on Harewood Street from September 25 until January 14 2019 Tunstall: Multi-way traffic lights on High Street near the Cheshire Cheese from October 28 until October 30 Tunstall: Roadworks and road closures on Lascelles Street from September 10 until November 5 Weston Coyney: Some carriageway incursion near number 276 from October 24 until October 26 Read MoreFestival Park is ready to welcome a new discount store (and it’ll even be selling clothes!) Newcastle Borough: Aston: Roadworks and road closure on Minn Bank from October 22 until October 23 Baldwins Gate/Blackbrook: Multi-way traffic lights at junction of A53 and A51 near The Swan with Two Necks from October 18 until October 22 Baldwins Gate: Multi-way traffic lights at Newcastle Road/Woodside from October 15 until October 26 Balterley: Two way traffic signals on B5500 Balterley Green Road near Back Lane on October 23 Betley: Two way traffic lights on Main Road near Mere Cottage from October 25 until October 29 Bradwell: Two way traffic lights along Bradwell Lane until November 30 Madeley Park: Two way traffic lights on Manor Road from October 18 until October 24 Newcastle: Multi-way traffic lights on Higherland and Drayton Street from October 26 until November 8 Newcastle: Roadworks and road closure on A53 King Street near the Borough Arms hotel from October 12 until November 15. Newcastle: Carriageway incursion on B5044 Silverdale Road near Silverdale Motors from October 15 until October 26 Porthill: Multi-way traffic signals on Oakland Avenue and Inglewood Drive from September 17 until November 1 Reginald Mitchell Way: Give and take traffic controls on Reginald Mitchell Way near the A500 from October 25 until October 29 Silverdale: Multi-way traffic lights on High Street from junction with Mill Street to Parkfields Close from September 7 until October 18 Silverdale: Roadworks and Road closure on Hollywood Lane until March 20 2019 Read MoreTrainee accountant injured two cyclists while trying to overtake at junction – and one was left with FOUR fractures to his pelvis Staffordshire Moorlands: Biddulph: Two way traffic signals on Woodhouse Lane from October 23 until October 26 Cheadle: Multi-way traffic lights on Tape Street outside number 79 from October 22 until October 24 Forsbrook: Two way traffic signals on Draycott Old Road from September 26 until October 26 Hollington: Two way traffic signals on Main Road outside the Old Smithy from March 14 until December 4. Ipstones: Roadworks and road closure on Belmont Road from October 22 until October 26 Kingsley: Two way traffic signals on Holt Lane in Kingsley from October 17 until October 23 Leek: Multi-way traffic signals on Abbotts Road from September 10 until November 1 Leek: Multi-way traffic signals at junction of Ball Haye Green, Haregate Road and Novi Lane from September 10 until November 1 Leek: Multi-way traffic signals on Broad Street at junction with Hartington Street on October 22 Leek: Roadworks and road closures on Brunswick Street from October 8 until October 29 Leek: Roadworks at junction of Buxton Road and Prince Street until November 7 Leek: Multi-way traffic signals at junction of Carlton Terrace near junction with Prince Street from October 12 until November 8 Leek: Give and take traffic control on A53 Newcastle Road near Woodcroft Avenue from October 22 until October 29 Leek: Traffic lights on Osborne Street until November 2 Rudyard: Two way traffic signals on A523 Macclesfield Road from October 15 until November 2 outside Packsaddle Hollow Rushton Spencer: Two way traffic signals on Leek Old Road from Hillside to Outside Rivendell on October 26 Warslow: Multi-way traffic lights on Longnor Road, Leek Road and Onecote Road on October 26 Whiston: Two way traffic signals near Leys House on Main Road on October 25 Whiston: Black Lane closed for work to be carried out on disused railway bridge from September 17 until October 26 Read MoreThis city centre car park is closing for THREE months (but it’s good news for Winter Wonderland!) Stafford Borough: Adbaston: Roadworks and road closure on Main Road near Marsh Meadow from October 22 until November 23 Beffcote (near Gnosall): Stop/go boards on Gnosall Road near the Adstones from October 19 until October 23 Bradley: Two way signals on Mitton Road from October 19 until October 23 Cocknage: Roadworks and road closure on Barlaston Road from junction with Cocknage Road to Woodpark Lane from October 24 until October 26 Creswell: Two way traffic signals on A5013 Creswell Grove outside number 28 from October 22 until October 24 Creswell: Two way traffic signals on A5013 Eccleshall Road outside Woodhouse Holdngs from October 23 until October 29 Eccleshall: Roadworks and road closure on Green Lane from October 15 until November 9 Eccleshall: Carriageway incursion on B5026 Stone Road near number 24 from October 18 until October 30 Ellenhall: Two way traffic signals on Bridle Lane from October 15 until October 26 Fulford: Two way signals on Fulford Road opposite Sandyrocks from October 17 until October 25 Haughton: Multi-way traffic signals on Newport Road outside Royds Close on October 28 Hilderstone: Two way signals on B5066 Sandon Road outside Field House from October 19 until October 23 Great Haywood: Two way signals on Little Tixall Lane near the A51 on October 22. Meaford: Roadworks and road closure at canal bridge on Rookery Lane from October 8 until October 28 Rough Close: Two way signals on Windmill Hill outside Heath Cottage from October 24 until October 26 Stone: Roadworks and some overnight closures at Aston Roundabout from August 20 until November 2 Stone: Two way signals on Eccleshall Road B5026 from October 22 until October 26 Stone: Multi-way traffic signals on Lichfield Road from October 26 until October 29 Stone: Two way signals on B5027 Newcastle Road outside number 154 from October 22 until October 25 Spotacre: Two way signals on B5066 Hilderstone Road outside Stanley House Farm from October 23 until October 25 Stafford: Roadworks and road closure on Baswich Lane near the canal bridge from September 10 until December 14 Stafford: Temporary traffic lights on Beaconside until April 2019 Stafford: Two way signals on Cannock Road near the new development at the police HQ site from October 25 until November 6 Stafford: Multi-way traffic signals on Drummond Road from October 15 until November 30 Stafford: Two way traffic signals on A5013 Eccleshall Road from October 22 until November 2 Stafford: Multi-way signals on Parkside Avenue at junction with Aldershaw Close from October 22 until November 2 Stafford: Two way signals on Shackleton Way from October 24 until November 6 Stafford: Roadworks and road closures on Shakespeare Road, Coleridge Drive, Tennyson Road and Somerset Road from August 6 until November 9 Stafford: Give and take traffic control on Silkmore Lane between numbers 195 and 201 from October 18 until October 22. Stafford: Roadworks and road closure on Thorneyfields Lane in Castle Bank over M6 until April 2019 Stafford: Carriageway incursion on Tipping Street on October 23 Stafford: Two way signals on West Way near junction with Coleridge Drive from October 12 until October 25 Weston: Two way signals on Weston Bank near junction with Brick Kiln Lane on October 28 There’s still time for you to object to this McDonald’s having a 24-hour drive-thru – here’s how Uttoxeter and surrounding areas of East Staffordshire: Doveridge: Give and take traffic control on Derby Road from October 22 until October 24 Rocester: Two way signals on Dove Lane from October 22 until October 26 Rocester: Two way traffic signals on Station Road near junction with Woodseat from October 24 until October 26 Uttoxeter: Multi-way traffic lights on Balance Street from October 21 until October 24. Uttoxeter: Give and take traffic control on Carter Street from October 21 and October 24 Uttoxeter: Two way signals on A522 New Road from October 24 until October 26 Uttoxeter: Multi-way traffic signals from the junction with the A522 New Road and Bentley Road to the access into JCB World Parts Centre until November 18. Uttoxeter: Roadworks and road closure on A522 from October 4 until January 18 2019. Rugeley: Rugeley: Give and take traffic control on Sandy Lane from October 25 until October 26 Rugeley: Multi-way traffic signals on Heron Street at junction with Forge Road from October 22 until October 24 Read More’It’s like a ghost town’ – Barber to shut up shop after 22 YEARS in town centre South Cheshire: A500: Lane closure at Mermeoor Roundabout/Shavington bypass from October 25 until October 26 A500: Lane closure at Crewe Green Link Roundabout from October 25 until October 26 A500: Lane closure at Shavington Bypass Roundabout in Shavingtom Cum Gresty from October 25 until October 26 A500: Lane closure at Cheerbrook roundabout from October 25 until October 26 Alsager: Multi-way signals on B5078 Chells Hill in Betchon at the junction of Sandbach Road from October 22 until November 9 Alsager: Carriageway incursion on Close Lane from October 10 until October 29 Alsager: Multi-way traffic signals on Hellyar Brook Road at the junction with Dunnocksfold Road from October 17 until October 23 Alsager: Carriageway incursion on Linley Road on October 22 Alsager: Stop/go boards on Pikemere Road on October 22 Betchton: Two way traffic signals on A50 Newcastle Road over Lynnhouse Bridge Bosley: Two way traffic lights on Tunstall Road near Bosley Wood Treatment until February 2019. Congleton: Carriageway incursion on Longdown Road from October 17 until October 23 Congleton: Roadworks and road closure on Fol Hollow from A34 Newcastle Road until Bankyfields Crescent from October 16 until October 24 Congleton: Two way traffic signals on A527 Park Lane from October 19 until October 25 Congleton: Carriageway incursion on Walfield Avenue from October 15 until October 30 Crewe: Multi-way traffic signals at junction of Bleasdale Road and Rydal Mount from October 18 until November 1 Crewe: Carriageway incursion on Broughton Road from September 24 until November 2 Crewe: Ongoing roadworks at Crewe Green Roundabout until December 1 Crewe: Carriageway incursion on A534 Crewe Road from October 18 until October 22 (outside number 332) Crewe: Two way traffic signals on Dunwoody Way from Dunwoody Way Roundabout from October 22 until November 16 Crewe: Road closures and roadworks on Franklyn Avenue from October 22 until October 24 Crewe: Give and take traffic control on Hungerford Road near number 339A from October 25 until October 26 Crewe: Carriageway incursions and road closures on Mablins Lane near Sunnyside Place until November 4 Crewe: Roadworks on Maw Green Road until October 31 Crewe: Multi-way traffic signals at junction Middlewich Road/Wistaston Green Road from July 23 until October 25. Crewe: Give and take traffic control on Middlewich Street from October 19 until October 22 Crewe: Stop/go boards on A5019 Mill Street from October 26 until October 29 Crewe: Stop/go boards on Moreton Road from October 17 until October 23 Crewe: Give and take traffic control on Nelson Street from October 22 until October 24 Crewe: Multi-way traffic signals on Parkers Road near the Eight Farmers from October 15 until October 29 Crewe: Roadworks and road closure on Ruskin Road on October 22. Crewe: Roadworks and traffic signals at junction of Somerville Street/Lunt Avenue and Claremont Road until October 29 Crewe: Sydney Road closed from midnight on Saturday October 26 until 7am on Sunday October 27 Crewe: Roadworks and road closure on A532 West Street on October 22 Crewe: Two way signals on West Street outside number 268 from October 24 until October 30 Crewe: Carriagewway on West Street near junction of Frank Webb Avenue on October 27 Crewe: Roadworks and road closure on Wheatley Road from October 22 until October 23 Crewe: Roadworks and road closure around the railway bridge on Wistaston Road from September 20 until November 11 Hough: Two way traffic signals on Cobbs Lane from October 26 until October 30 Hough: Two way traffic signals on Newcastle Road from October 23 until October 26 Minshull Vernon: Two way traffic signals on Eardswick Lane near High Farm from October 24 until October 26 Moreton: Two way traffic signals near junction with Newcastle Road from October 22 until October 24 Nantwich: Multi-way traffic lights at junction of Arnhold Street and Cowfields from October 23 until October 25. Nantwich: Stop/go boards on Blankney Avenue on October 22 Nantwich: Stop/go boards on Edmund Wright Way from September 28 until November 2 Nantwich: Roadworks overnight at level crossing on B5074 London Road from October 25 until October 26 Nantwich: Carriageway incursions on A530 Peter Destapleigh Way from October 1 until October 26 Nantwich: Carriageway incursion on Pillory Street on October 28 Nantwich: Two way signals on Wybunbury Lane at the side of the Cedars from October 24 until October 26 Odd Rode: Multi-way traffic signals at junction of Grays Close and The Bank from October 15 until October 26 Rode Heath: Stop/go boards on Heath Avenue on October 22 Sandbach: Carriageway incursion on Bradwall Road near junction with Chapel Street from October 24 until October 26 Sandbach: Plant Lane closed at Canal Bridge on October 24 and October 26 Sandbach: Multi-way traffic lights on A534 Congleton Road at the junction with Holmes Chapel Road on October 28 Sandbach: Carriageway incursion on High Street near numbers 40-42 from October 21 until October 23. Sandbach: Two way signals on A533 Middlewich Road near Turnpike Court and Co-op from October 25 until October 26 Sandbach: Carriageway incursion on B5079 Station Road near Moss Lane from October 22 until November 5 Scholar Green: Roadworks and road closures at the canal birdge on Little Moss Lane from September 26 until October 24 Scholar Green: Road closure on Nursery Lane on October 27 Smallwood: Road closure on Church Lane on October 26 Somerford: Carriageway incursion on A54 Holmes Chapel Road at Braken Barns from October 22 until October 26 Stapeley: Stop/go boards on A529 Broad Lane near Primary School on October 24 Stapeley: Two way traffic signals on First Dig Lane from October 19 until October 25 Wildboarclough: A54 Buxton Road closed in both directions until November 4. Willaston: Carriageway incursion on Cheerbrook Road from October 22 until October 24 Willaston: Multi-way traffic signals at junction of Wybunbury Road and Cheerbrook Road from October 26 until October 30 Willaston: Roadworks and lane closure at Peacock Roundabout (Crewe Road/Nantwich Bypass) until October 7 Willaston: Roadworks and road closure at level crossing on Wistaston Road on October 28 Willaston: Carriageway incursion on Wistaston Road near junction with Moorfields and Gladstone Street from October 24 until October 26 Wybunbury/Shavington: Roadworks and road closure on Dig Lane from October 27 until October 29 Want to keep up to date with the latest traffic and travel news?Each day Stoke-on-Trent Live journalists bring you the latest news on the roads and railways across Stoke-on-Trent, North Staffordshire, South Cheshire and further afield to help keep you on the move. For the very latest updates on roads including the M6, A500, A50 and more, visit our dedicated traffic and travel news channel here. We also run a live news feed each weekday, which you can access on our website’s homepage from 7am to 9pm from Monday to Friday. And for more as-we-get-it updates on the roads across the region and beyond, join The Sentinel’s traffic and travel Facebook group here. Want to tell us about something going on where you live? Let us know – Tweet us @SOTLive or message us on our Facebook page . And if you have pictures to share, tag us on Instagram at StokeonTrentLive . Newcastle Borough